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Odontologi/farmasi.

Periodonti for masterstudenter og spesialistkandidater.

1.   Hoffman J, Lindberg B, Hofstad T, Lygre H. Structural studies of the polysaccharide antigen of Eubacterium saburreum, strain L 452. Carbohydrate Research 1977;58:439-442.

2.   Hofstad T, Lygre H. Composition and antigenic properties of a surface polysaccharide isolated from Eubacterium saburreum, strain L452. Acta Path Microbiol Scand Sect B 1977;85:14-17.

3.   Lygre H, Solheim E, Skaug N. Fatty acid content of human dental cementum and root dentin. J Dent Res 1990;69:271 (Special issue).

4.   Lygre H, Solheim E, Skaug N. Fatty acid content of human dental cementum and root dentin. Poster presented at the IADR conference in Washington March 1990.

5.   Lygre H, Solheim E, Gjerdet NR, Skaug N. Fatty acids of healthy and periodontally diseased root substance in human teeth. J Dent Res 1992;71:43-46.

6.   Lygre H, Solheim E, Gjerdet NR, Berg E. Leaching of organic additives from dentures in vivo. Acta Odontol Scand 1993;51:45-51.

7.   Lygre H, Solheim E, Gjerdet NR. Leaching from orthodontic resins processed by different techniques. J Dent Res 1994;73:950 (Special issue).

8.   Lygre H, Solheim E, Gjerdet NR. Leaching from orthodontic resins processed by diffent techniques. Poster presented at the IADR/NOF conference in Kolding, Denmark 1994.

9.   Lygre H, Klepp KN, Solheim E, Gjerdet NR. Leaching of additives and degradation products from cold-cured orthodontic resins. Acta Odontol Scand 1994;52:150-156.

10. Lygre H, Solheim E, Gjerdet NR. Leaching from denture base materials in vitro. Acta Odontol Scand 1995;53:75-80.

11. Lygre H, Solheim E, Gjerdet NR, Espelid M. Fatty acid composition of palatal tissue from denture stomatitis patients. Acta Odontol Scand 1995;53;249-253.

12. Lygre H, Moe G, Solheim E, Gjerdet NR. Biologic testing of leachable aromatic compounds from denture base materials. Acta Odontol Scand 1995;53:397-401.

13. Lygre H. Aromatic leachables from denture base materials. Thesis. University of Bergen, School of Dentistry, Department of Biomaterials. 1995.

14. Lygre H. Akrylplast. NTF`s Tidende 1997;107:340-341.

15. Lygre H, Solheim E, Høl PJ. Organic leachables from polymer-based dental filling materials. J Dent Res 1998;77:818 (Special issue B).

16. Lygre H, Solheim E, Høl PJ. Organic leachables from polymer-based dental filling materials. Poster presented at the IADR conference in Nice, France 1998.

17. Lygre H. Refleksjon over målbeskrivelse, pensum, undervisningsformer og evalueringsformer ved tannpleierstudiet, DOF, ���ϳԹ���Դ. UPED-skrift 1998;2:107-117.

18. Lygre H. Bivirkninger av oralprotetiske materialer. Scandinavian Society of Prosthetic Dentistry. 1999:1-34. Rapport från undervisningskommiten.

19. Lygre H, Høl PJ, Solheim E, Moe G. Organic leachables from polymer-based dental filling materials. Eur J Oral Sci 1999;107:378-383.

20. Vik H, Berntsen A, Petterson B, Lygre H: Interaction of DMABEE and glycerophospholipid monolayer. Poster presented at the Dentsply Competition for Nordic Dental Students in Copenhagen March 2001.

21. Michelsen VB, Skålevik R, Tveit AB, Lygre H. Identification of organic eluates from four polymer-based dental filling materials. J Dent Res 2001;80:756 (Special issue). Abstract presented at the IADR conference in Chiba, Japan, 2001.

22. Michelsen VB, Skålevik R, Tveit AB, Lygre H, Solheim E. Identification of organic eluates from four polymer-based dental filling materials.  Poster presented at the IADR conference in Chiba, Japan, 2001.

23. Lygre H, Vorland M, Holmsen H. Interaction of a dental filling eluate and membrane lipids. Clin Oral Invest 2001;5:167-171.

24. Lygre H. Prosthodontic biomaterials and adverse reactions: a critical review of the clinical and research literature. Acta Odontol Scand 2002;60:1-9.

25. Lygre H, Moe G, Skålevik R, Berntsen A, Kha D, Giertsen E. Interaction between triclosan and membrane lipids. Poster presented at the 7^th IUBMB Conference on RECEPTOR-LIGAND INTERACTIONS. Molecular, Physiological and Pharmacological Aspects. Bergen 4-8 May 2002.

26. Michelsen VB, Skålevik R, Lygre H, Tveit AB, Solheim E. Quantification of eluates from polymer-based dental filling materials. Poster presented at the Pan European Federation of IADR meeting, Cardiff, UK 25-28 September 2002.

27. Lygre H, Moe G, Skålevik R, Holmsen H. Interaction of triclosan with eukaryotic membrane lipids. Eur J Oral Sci  2003;111:216-222.

28. Michelsen V, Lygre H, Skålevik R, Tveit AB. Identification of organic eluates from four polymer-based dental filling materials. Eur J Oral Sci 2003;111:263-271.

29. Cimpan MR, Matre R, Skaug N, Sørnes S, Lygre H. 4-N,N-dimethyl Amino Benzoic Acid Ethylester Induces Apoptosis and Necrosis in U937 Cells. J Dent Res 2003, 82 (Special issue) B-343. Abstract presented at the IADR meeting in Gothenburg, Sweden 25-28 June 2003.

30. Cimpan MR, Matre R, Skaug N, Sørnes S, Lygre H. 4-N,N-dimethyl Amino Benzoic Acid Ethylester Induces Apoptosis and Necrosis in U937 Cells.  Poster presented at the IADR meeting in Gothenburg, Sweden 25-28 June 2003.

31. Lygre H, Moe G, Holmsen H. Interaction of ibuprofen with eukaryotic membrane lipids. Acta Odontol Scand 2003;61:303-309.

32. Bruk av smertestillende medikamenter I tannlegepraksis. Anne Bue og Kristin Grytten. Prosjektoppgave i odontologi. ���ϳԹ���Դ 2003.

33. Hvilke legemidler gir zerostomi og hvorfor? Phuong Tran. Prosjektoppgave i odontologi. ���ϳԹ���Դ 2004.

34. Xerostomi. Hong-Thuy Thi Nguyen. Prosjektoppgave i odontologi. ���ϳԹ���Դ 2004.

35. Xerostomi – med hovedvekt på den medikamentinduserte. Lien T.T.Nguyen og Jan Roar Rønning. Prosjektoppgave i odontologi. ���ϳԹ���Դ 2004.

36. Vekselvirkning mellom membraner og triklosan. Anders Berntsen. Prosjektoppgave i odontologi. ���ϳԹ���Դ 2004.

37. Potensielle legemiddelinteraksjoner i tannlegepraksis. Prosjektoppgave i odontologi. Kari J. Sigdestad og Monika Skogstrand. ���ϳԹ���Դ 2004. 

38. Cimpan MR, Matre R, Skaug N, Lie SA, Lygre H. The co-initiator DMABEE induces death by apoptosis and necrosis in human monoblastoid cells. Clin Oral Invest 2005:9;168-172.

39. Michelsen VB, Moe G, Lygre H. Plastfyllinger lekker – hva skjer? Scan News 22.08.2005.

40. Lygre H, Moe G, Theodorsen A, Tuven V, Holmsen H. Articaine hydroklorid interaction with eukaryotic membrane lipids. Abstracts Book. ISSN 0145-5680, page 50. 4^th World Congres of CELLULAR AND MOLECULAR BIOLOGY ^TM. Poitiers – France, 7-12 October, 2005. Abstract.

41. Lygre H, Moe G, Theodorsen A, Tuven V, Holmsen H. Articaine hydroklorid interaction with eukaryotic membrane lipids. 4^th World Congress of Cellular and Molecular Biology”. Poitiers – France, 7-12 October, 2005. Oral presentation.

42. Smertebehandling i odontologi ved hjelp av analgetika. Laila Johansen, Kine Bang Nilsen og Anita Hines. Prosjektoppgave i odontologi. ���ϳԹ���Դ 2006.

43. Michelsen VB, Moe G, Strøm MB, Jensen E, Lygre H. Kvantifisering av utløste substanser fra polymerbaserte fyllingsmaterialer – analyser med GC/MS. Biomaterial Network Meeting, NIOM, Haslum, Oslo, 11.08.2006.

44. Rød J, Lygre H. Når tannlegen mistenker legemiddelbivirkninger. NTF`s Tidende 2006; 116: 286-287.

45. Michelsen VB, Skålevik R, Jensen E, Lygre H. Quantification of organic eluates from polymerized resin-based dental restorative materials by use of GC/MS. J Chromatogr B Analyt Technol Biomed Life Sci 2007;850:83-91.

46. Lygre H, Reuter N, Rødland I. Bioinformatikk anvendt på lokalanestetikas virkningsmekanisme. NTF´s Tidende 2007;117:672-675.

47. Michelsen, Vibeke Barman; Strøm, Morten Bøhmer; Jensen, Einar; Moe, Grete; Lygre, Henning. GC-MS ANALYSE AV UTLEKKSSTOFFER FRA POLYMERBASERTE DENTALE FYLLINGSMATERIALER [Vitenskapelig foredrag]. 12. Norsk seminar i massespektrometri; 21.01.2007 - 24.01.2007

48. Song, Chen; Lygre, Henning; Nerdal, Willy. Articaine interaction with DSPC bilayer: a C-13 and P-31 solid-state NMR study. Chemistry and Physics of Lipids 2007;149 Suppl 1:S43-S43. Abstract.

49. Michelsen VB, Moe G, Strøm MB, Jensen E, Lygre H. Quantitative analysis of TEGDMA and HEMA eluted in saliva from two dental composites by use of GC/MS and tailor-made internal standards. Dental Materials 2008;24:724-731.

50. Song C, Lygre H, Nerdal W.Articaine interaction with DSPC Bilayer: A ¹³C and ³¹P Solid-State NMR Study. Eur J Pharm Sci 2008;33:399-408.

51. Al-Haroni M, Lygre H, Bakken V. Antibiotikaresistens hos orale bakterier. NTF´s Tidende 2008;118:704-8.

52. Pedersen IB, Skjevik ÅA, Lygre H, Teigen K. Drug-membrane interactions. An explanation for the anti-inflammatory effect of local anesthetics? Poster presented at the 44^th Meeting of the Norwegian Biochemical Society, January 17-20, 2008, Lillehammer, Norway.

53. Pedersen IB. Biological targets of local anaesthetics – A molecular modelling study. Masteroppgave i farmasi. Institutt for biomedisin. Institutt for indremedisin. ���ϳԹ���Դ. Mai 2008. B til eksamen.

54. Skjevik ÅA. Interaction of a local anaesthetic with membrane lipids studied by computer modelling. Masteroppgave i farmasi. Institutt for biomedisin. Institutt for indremedisin. ���ϳԹ���Դ. Mai 2008. A til eksamen.

55. Lokalanestesi og inflammatorisk respons. En ny terapeutisk indikasjon? Tonje Mjanger og Solveig Omland. Integrert masteroppgave i odontologi. ���ϳԹ���Դ 2008.

56. Skjevik ÅA, Pedersen IB, Lygre H, Teigen K. Interactions between the local anesthetic articaine and membranes: A theoretical and experimental study. Abstract accepted for the 33th FEBS Congress & 11^th IUBMB Conference, June 28- July 3, 2008, Athens, Greece.

57. Skjevik ÅA, Pedersen IB, Lygre H, Teigen K. Interactions between the local anesthetic articaine and membranes: A theoretical and experimental study. Poster presented at the 33th FEBS Congress & 11^th IUBMB Conference, June 28- July 3, 2008, Athens, Greece.

58. MichelsenVB, Moe G, Kopperud HBM, Kleven IS, Lygre GB, Svahn J, StrømMB, Bjorkman L, Jensen E, Lygre H. Monomers detected in saliva after treatment with composite fillings. Abstract accepted for the PEF IADR Conference in London,10-12 September 2008.  J Dent Res.

59. MichelsenVB, Moe G, Kopperud HBM, Kleven IS, Lygre GB, Svahn J, StrømMB, Bjorkman L, Jensen E, Lygre H. Monomers detected in saliva after treatment with composite fillings. Poster presented at the PEF IADR Conference in London, 10-12 September 2008.

60. Skjevik Å, Lygre H, Teigen K. Interaction of a local anaesthetic with lipid membranes studied by computer modelling. Abstract accepted for the NBCR (National Biomedical Computational Resource), Summer Institute, Cyberinfrastructure for Biomedicine, La Jolla, California, 4-8 august, 2008.

61. Skjevik Å, Lygre H, Teigen K. Interaction of a local anaesthetic with lipid membranes studied by computer modelling. Poster presented at the NBCR (National Biomedical Computational Resource), Summer Institute, Cyberinfrastructure for Biomedicine, La Jolla, California, 4-8 August, 2008.

62. Lygre H, Moe G, Nerdal W, Holmsen H. Interaction of articaine hydrochloride with prokaryotic membrane lipids. Acta Odontol Scand 2009;67:1-7.

63. Skjevik ÅA, Pedersen IB, Lygre H, Teigen K. Molecular dynamics simulation: Interaction between the local anaesthetic articaine and membrane models. Poster presented at Keystone Symposia on Molecular and Cellular Biology, Keystone, Colorado, 5-10 June, 2009.

64. Lygre H. Periodonti og farmakologi – finnes en ny klinisk vri?  Oral presentasjon ved Vestlandsmøtet (NTF) 2010, Bergen, Norge, 2010-01-07 – 2010-01-09.

65. Mustafa M, Kantarci A, Bolstad AI, Lygre H, Mustafa K, Serhan CN, van Dyke TE.  Resolvin D1 reduces prostaglandin E₂ and increase lipoxin A₄ production in human periodontal ligament cells. Abstract accepted at 88the General Session & Exhibition of the IADR in Barcelona, Spain 2010-14-07 – 2010-17-07

66. Mustafa M, Kantarci A, Bolstad AI, Lygre H, Mustafa K, Serhan CN, van Dyke TE.  Resolvin D1 reduces prostaglandin E₂ and increase lipoxin A₄ production in human periodontal ligament cells. Poster presented at 88the General Session & Exhibition of the IADR in Barcelona, Spain 2010-14-07 – 2010-17-07

67. Mustafa M, Kantarci A, Bolstad AI, Lygre H, Mustafa K, Serhan CN, van Dyke TE. Resolvin D1 reduces prostaglandin E2 and increase lipoxin A4 production in human periodontal ligament cells. Oral presentation at 88the General Session & Exhibition of the IADR in Barcelona, Spain 2010-14-07 – 2010-17-07

68. Skjevik ÅA, Lygre H, Teigen K. Can intramolecular hydrogen bonding in articaine be related to superior bone tissue penetration? A molecular dynamics study. Poster presented at “Dental Research Day” November 5^th 2010, BBB, UoB.

69. Skjevik ÅA, Haug BE, Lygre H, Teigen K. Intramolecular hydrogen bonding in articaine can be related to superior bone tissue penetration. A molecular dynamics study. Biophys Chem 2011;154:18-25

70. Lygre H. Periodontal sykdom og bioaktive lipider. Nor Tannlegeforen Tid 2011;121:832-836

71. MichelsenVB, Kopperud HBM, Kleven IS, LygreGB, Svahn J, Bjorkman L, Jensen E, LygreH. Detection and quantification of monomers in unstimulated whole saliva after treatment with composite fillings in vivo. Eur J Oral Sci. 2012;120:89-95

72. Lygre H. Periodontal sykdom og bioaktive lipider. Revmatikeren 2012;2:23.

73. Rosenbaum PE, Mikalsen O, Lygre H, Solheim E, Schjøtt JD. A blended learning course design in clinical pharmacology for postgraduate dental students. The Open Dentistry Journal. 2012;6:182-187

74. Mustafa M, Zarrough A, Bolstad AI, Lygre H, Mustafa K, Hasturk H, Serhan CN, Kantarci A, van Dyke TE. Resolvin D1 Protects Periodontal Ligament. Am J Physiol Cell Physiol. 2013;305(6):C673-9.

75. Lygre H. Odontologisk farmakologi og den aldrende befolkning. Foredrag NTFs Landsmøte, Lillestrøm, 31 oktober 2013.

76. Skoglund LA, Lygre H. Tannhelsesekretærer og odontologisk lokalanestesi. Nor Tannlegeforen Tid. 2014;124:318-19.

77. Lygre H. Legemiddelindusert gingival overvekst (LIGO) – forekomst, patologi og klinikk. Nor Tannlegeforen Tid. 2014;124:370-75.

78. Kirkengen AL, Lygre H. Exploring the Relationships between Childhood Adversity and Oral Health: An anecdotal Approach and Integrative View. Medical Hypotheses 2015;85:134-140.

79. Raknes RB. Registrering av legemiddelbruk i pasientjournal for tannhelseopplysninger. Masteroppgave i farmasi. Senter for farmasi. ���ϳԹ���Դ 2014. 45 studiepoeng. B til eksamen.

80. Raknes RB, Lygre H, Klock K, Haavik S, Kjome RLS.  Registrering av legemiddelbruk i tannhelsejournal. Nor Tannlegeforen Tid 2015;125:626-632.

81. Ressem SL. Pasienten som tannlegens kilde til legemiddelopplysninger – en kartleggingsstudie ved private tannhelseklinikker i Bergen. Masteroppgave i farmasi. Senter for farmasi. ���ϳԹ���Դ 2014. 45 studiepoeng. B til eksamen.

82. Ressem SL, Klock KS, Haavik S, Lygre H, Kjome RLS. Pasienten som tannlegens kilde til legemiddelopplysninger – en kartleggingsstudie ved private tannhelseklinikker i Bergen. Nor Tannlegeforen Tid. Submitted March 2015. 

83. Lygre H, Kjome RLS. Aldring, sykdom og legemiddelbruk. Bokkapittel i Odontologi 16. In press.

84. Suliman S, Xing Z, Wu X, Xue Y, Pedersen TØ, Sun Y, Døskeland A, Nickel J, Waag T, Lygre H, Finne-Wistrand A, Steinmüller-Nethl, Krueger A, Mustafa K. Release and bioactivity of bone-morphogenetic protein-2 are affected by scaffold binding technique in vitro and in vivo. Journal of Controlled Release 2015;197:148-157.

85. Gingival overvekst ved bruk av kalsiumantagonister. Sylvia Lid og Lise Marthe Krogenes. Masteroppgave i odontologi. ���ϳԹ���Դ 2015.

86.  Bruk av reseptfrie smertestillende legemidler ved tannregulering av barn og unge 8-18 år. Magnus Rogne Halland og Åsmund Heggen Pedersen. Masteroppgave i odontologi. ���ϳԹ���Դ 2015.

87. Fardal Ø, Lygre H. Management of periodontal disease in patients using calcium channel blockers – gingival overgrowth, prescribed medications, treatment responses and added treatment costs. J Clin Periodontol 2015;42:640-646 (Level 2).

88. Lygre H. Amlodipin-induced gingival overgrowth. Review. Manuscript. 

89. Lygre H. Måling av kortisol i saliva. Nor Tannlegeforen Tid 2016;126:684-7.

90. Forebygging av legemiddelindusert osteonekrose i kjeveben. Tina Isabel Hansen og Lena Kristin Barstad. Bacheloroppgave i tannpleie. Seksjon for forebyggende tannhelse, IKO, ���ϳԹ���Դ 2015.

91. Sandberg A. Tannhelsetjenesten og informasjon om legemiddelbruk. Masteroppgave i farmasi. Senter for farmasi. ���ϳԹ���Դ Mai 2016. 45 studiepoeng. A til eksamen.

92. Sandberg A. Lygre H, Kjome RLS. Tannhelsetjenesten og informasjon om legemiddelbruk. Submitted. Norw Dental J. 2016.

93. Lygre H. Kalsiumantagonister og periodontal sykdom. Nor Tannlegeforen Tid 2015;125:810.

94. Lygre H. Kalsiumantagonister og periodontal sykdom. Tidsskr Nor Legeforen 2016. Submitted.

95. Lygre H, Kjome RLS, Choi H, Autumn S. Dental providers and pharmacists: a call for better interprofessional collaboration. International Dental Journal 2017;67:329-331.

96. Staniszewski K, Kvinnsland S, Helgeland E, Willasen L, Berge T, Johansson A, Schjødt B, Bell RF, Paulsberg AG, Geitung JT, Aandal G, Lygre H. Rosén A. Temporomandibular disorders with a psychososial approach: Preliminary data from a clinical case-control study. Abstract at the TMD symposium at Solstrand, Os ved Bergen, June 1-3, 2016.

97. Staniscewski K, Kvinnsland S, Helgeland E, Willasen L, Berge T, Johansson A, Schjødt B, Bell RF, Paulsberg AG, Geitung JT, Aandal G, Lygre H, Rosén A. Temporomandibular disorders with a psycosocial approach: Preliminary data from a case-control study. Poster at the TMD symposium at Solstrand, Os ved Bergen, June 1-3, 2016.

98. Staniszewski K, Lygre H, Rosén A. Temporomandibular disorders with a psychosocial approach: Preliminary data from a case-control study. Oral presentation. Svenska Riksstämnan, Stockholm November 2016.

99. Staniszewski K, Kvinnsland S, Helgeland E, Willasen L, Berge T, Bifulco E, Lygre H, Rosén A. Temporomandibular disorders related to HPA-axis regulation: A clinical cross-sectional study. Submitted to J Dent Res 2017.

100. Lygre H. «Tannhelse og legemidler» eller «Legemidler og bivirkninger i munnhulen». Oversiktsartikkel til Norsk Farmaceutisk Tidsskrift 2017.

101. Stamceller – ei behandlingsmogeligheit i odontologi? Hilde Ramsevik Riksem og Anna Elise Aklestad. Masteroppgave i odontologi, IKO, ���ϳԹ���Դ 2017.

102. Bjønnes J. Norske tannlegers legemiddelforskrivning. Masteroppgave i farmasi. Senter for farmasi, ���ϳԹ���Դ 2017. 45 studiepoeng.

103. Haver H, Bang T, Lønning H, Lygre H. Implementering av kunnskapsbasert praksis i odontologi. En studie ved bruk av radiolog som rollemodell. Submitted to. Nor Tannlegeforen Tid 2017.

104. Design og produksjon av prototype av individuell totaltannbørste for sykehjemspasienter. Vy Thank Huynh og Kristian Vårdal. Bacheloroppgave i tannpleie, IKO, ���ϳԹ���Դ, 2017. Kåret til beste bacheloroppgave ved IKO i 2017.

105. Kirkengen AL, Lygre H. Possible relationship between childhood adversity and oral health. 20^th Nordic Congress in General Practice, Reykjavik, Iceland, June 14-17,2017.

106. Lygre H, Bjønnes JAJ, Lie SA, Kjome RLS. Prescriptions from Norwegian dental providers from 2004-2015. Manuscript for submission to Acta Odontologica Scandinavica 2018. 

Norske tannlegers legemiddelforskrivning

Anti-inflammatory effects from local anesthetics