Microfluidic platform for real-life exposure to nanomaterials
The microscopy setup consists of a BioStation IM (Nikon) with automated XYZ stage, temperature and CO2 control for incubation of living cells. Impedance is monitored in real-time with a LCR meter (HIOKI). The platform is equipped with a OB1 MK4 pressure flow controller (Elveflow). Microfluidic chips and Au-microelectrode arrays are designed and made in-house at the clean-room facilities of the Dept. of Physics and Technology (黑料吃瓜资源).
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3D biological models
Advanced in-vitro models to study the interaction of nanomaterials with biological systems
We develop organ-on-a-chip models to understand how nanomaterials interact with biological systems. We develop symplistic, but reliable models to limit/replace the use of animals for testing of nanomaterials present in consumer products and medical devices including nanopharmaceuticals.
Label-free impedance-based and electrochemical methods
Impedance-based high throughput nanotoxicity screening on adherent and single cells.
Label-free: Impedance based biosensor technology does not require markers or dyes. Interference-free from Nanomaterials and Nanoparticles perturbation.
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HORIZON2020 EU Project "RiskGone"
WP5 co-lead and PI: Mihaela Roxana Cimpan, Professor; Researcher: Ivan Rios-Mondragon, PhD; Ying Xue, PhD; H氓kon Van Ta, MSc Nano; Arnaud Lemelle, PhD; Anne Marthe Dr酶nen, BSc
NANO2021 RCN project "NanoBioreal"
Research School for Training the Next Generation of Micro- and Nanotechnology Researchers in Norway (TNNN)
WP leader and Board member: Mihaela Roxana Cimpan, Professor
EEA Project "TEPCAN"
WP leader, PI: Mihaela Roxana Cimpan, Professor; Researcher: Ivan Rios-Mondragon, PhD
ANR project "NanoMilk"
WP leader, PI: Mihaela Roxana Cimpan, Professor; Coordinator: Anne Burtey, PhD (INRAE, Paris); Researcher: Ivan Rios-Mondragon, PhD; Marie Simon, PhD cand (INRAE, Paris).
Use of nanomaterials: Perception and hazard
Use of nanomaterials in dentistry- perceptions among dental personel and effects on a 3D oral mucosal model.
Collaborating institutions: Department of Clinical Dentistry, UoB, Clinical Institute (K1), Competence Center for Dental Expertise, TK Vestland.
PhD student: Victoria Xenaki
Funding: University of Bergen, Public Dental Health Care Services, Norway
Connected to Professor Anne Nordrehaug 脜str酶m and Professor Mihaela Roxana Cimpan (IKO), Daniela Elena Costea (K1), Mihaela Cuida Marthinussen (TKVest).
Related Persons
UH-nett Vest Project: New methods for assessing the effects of nanomaterials, MRI and various stressors on cells
Mihaela Roxana Cimpan, Ivan Rios-Mondragon, Kamal Mustafa (IKO), Emil Cimpan, Alvhild Alette Bj酶rkum (HVL), Bodil Holst, Martin Greve (IFT), Beate Kluge og Karen Rosendahl (Haukeland University Hospital)
Effects of Artificial Saliva on Silica nanoparticles
Students: Ida Marlene Nyg氓rd and Caroline Skjennum
Supervisors: Asgeir B氓rdsen, Professor; Mihaela R. Cimpan, Professor
Senior engineer: Hanzhen Wen
Effects of Nanodiamond particles
Mohammed A. Yassin, Associate Professor; Mohammed Ibrahim, PhD; Mihaela R.Cimpan, Professor, Kamal Mustafa, Professor, Julia Schoelermann, PhD.